KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VCL
All Species:
13.64
Human Site:
S260
Identified Species:
30
UniProt:
P18206
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18206
NP_003364.1
1134
123799
S260
W
D
E
D
A
W
A
S
K
D
T
E
A
M
K
Chimpanzee
Pan troglodytes
XP_001147193
1046
114802
N258
A
S
I
D
S
K
L
N
Q
A
K
G
W
L
R
Rhesus Macaque
Macaca mulatta
XP_001118118
547
59720
Dog
Lupus familis
XP_536395
799
87306
V115
E
V
R
K
I
I
R
V
C
K
G
I
L
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q64727
1066
116699
S260
W
D
E
D
A
W
A
S
K
D
T
E
A
M
K
Rat
Rattus norvegicus
P85972
1066
116597
S260
W
D
E
D
A
W
A
S
K
D
T
E
A
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507189
734
80358
K49
M
K
I
F
V
T
T
K
N
S
K
S
Q
G
I
Chicken
Gallus gallus
P12003
1135
124542
S260
W
D
E
D
A
W
A
S
K
D
T
E
A
M
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122153
1131
124026
N260
W
D
E
D
A
W
A
N
K
K
D
T
E
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46037
961
106284
L259
Y
D
E
D
T
S
E
L
D
N
L
T
V
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P19826
1010
111904
D259
T
Y
D
E
D
E
W
D
A
D
N
V
T
V
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
47.7
63.4
N.A.
93.3
93
N.A.
62.5
93.2
N.A.
85.5
N.A.
42.1
N.A.
39.6
N.A.
Protein Similarity:
100
90.9
47.8
66.5
N.A.
93.9
93.5
N.A.
63.8
96.6
N.A.
93
N.A.
57.7
N.A.
56.7
N.A.
P-Site Identity:
100
6.6
0
0
N.A.
100
100
N.A.
0
100
N.A.
53.3
N.A.
26.6
N.A.
6.6
N.A.
P-Site Similarity:
100
40
0
0
N.A.
100
100
N.A.
0
100
N.A.
60
N.A.
46.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
46
0
46
0
10
10
0
0
37
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
55
10
64
10
0
0
10
10
46
10
0
0
0
0
% D
% Glu:
10
0
55
10
0
10
10
0
0
0
0
37
10
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
0
10
10
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
10
0
10
0
10
0
10
46
19
19
0
0
0
46
% K
% Leu:
0
0
0
0
0
0
10
10
0
0
10
0
10
19
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
37
19
% M
% Asn:
0
0
0
0
0
0
0
19
10
10
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
0
0
10
10
0
37
0
10
0
10
0
0
0
% S
% Thr:
10
0
0
0
10
10
10
0
0
0
37
19
10
0
0
% T
% Val:
0
10
0
0
10
0
0
10
0
0
0
10
10
10
0
% V
% Trp:
46
0
0
0
0
46
10
0
0
0
0
0
10
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _